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Colloquium: Optical Imaging of Blood Flow Dynamics in the Brain

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Colloquium by Patrick Drew (Penn State Center for Neural Engineering)
When
19 September 2013 from 4:00 PM to 5:30 PM
Where
117 Osmond Laboratory
Contact Name
Contact Phone
(814) 863-6673
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The brain dynamically regulates its blood flow in order to supply necessary oxygen and fuel to neurons. Changes in blood flow ('hemodynamic signals') can be used to infer changes in neural activity, and are extensively used to monitor brain function, both in response to external stimuli, as well as internally generated dynamics. Here, I will present recent advances made with two-photon laser scanning microscopy in understanding the microscopic basis of blood flow changes in the brain. I will also discuss how these hemodynamic signals are related to neural activity, and how these signals give insight into the ongoing mesoscale dynamics of the brain.

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